Considering sex as a biological variable in preclinical research
نویسندگان
چکیده
منابع مشابه
Considering sex as a biological variable in preclinical research.
In June 2015, the National Institutes of Health (NIH) released a Guide notice (NOT-OD-15-102) that highlighted the expectation of the NIH that the possible role of sex as a biologic variable be factored into research design, analyses, and reporting of vertebrate animal and human studies. Anticipating these guidelines, the NIH Office of Research on Women's Health, in October 2014, convened key s...
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In June 2015, the National Institutes of Health (NIH) announced a new policy highlighting the expectation that sex as a biological variable (SABV) be factored into research designs, analyses, and reporting of vertebrate animal and human studies. NIH-funded research grants and career-development grants are now under this new policy and the first scientific reviews are complete. Since implementat...
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The National Institutes of Health recently highlighted the significant role of sex as a biological variable (SABV) in research design, outcome and reproducibility, mandating that this variable be accounted for in all its funded research studies. This move has resulted in a rapidly increasing body of literature on SABV with important implications for changing the clinical practice of emergency m...
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Sex as a biological variable (SABV) is a key part of the new National Institutes of Health (NIH) initiative to enhance reproducibility through rigor and transparency. The SABV policy requires researchers to factor sex into the design, analysis, and reporting of vertebrate animal and human studies. The policy was implemented as it has become increasingly clear that male/female differences extend...
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In recent months, there has been a flurry of discussion regarding the importance of considering the sex of animals, primary cells, and even cell lines when performing preclinical studies. These conversations were highlighted in a recent editorial in Nature by Janine A. Clayton, Director of the National Institutes of Health Office of Research on Women’s Health, and Francis S. Collins, Director o...
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2016
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fj.201600781r